Share on Facebook Share on Twitter

Thread Rating:
  • 0 Vote(s) - 0 Average
  • 1
  • 2
  • 3
  • 4
  • 5
Seroprevalance; Increasing risks (heart)
#1
The NIH has a dashboard that shows seroprevalence in the US over time.  I wish they subdivided it by geographic regions.

The data only goes to the end of November (before the incredible Omicron surge).  If I understand their data, roughly 30% of the population showed evidence of having had COVID-19 before Omicron.  Obviously that number has jumped significantly.  I wouldn't be surprised if it were at 60%.

The question in my mind is, how many people are still (or again) very vulnerable to Delta & Omicron.  The current unmasking of America makes it trecherous for those of us who have been diligent, or lucky, enough to have avoided COVID-19.  Yes, we can continue to wear our masks, but others who may be shedding virus profusely, won't be.  Take your mask off to get a sip of water and you may just inhale a single droplet from an infected person that isn't wearing a mask.



In the news is very concerning report about cardiovascular disease, over a year after having recovered.

Quote:COVID-19 boosted the risk of all 20 cardiovascular ailments studied, including heart attacks, arrhythmias, strokes, transient ischemic attacks, heart failure, inflammatory heart disease, cardiac arrest, pulmonary embolism, and deep vein thrombosis.

For example, veterans who had had COVID-19 faced a 72% higher risk of heart failure after 12 months than those in a control group who didn’t test positive. That translated to nearly 12 more infected people per 1000 developing heart failure than those in a control group. Overall, the investigators found 45 more infected people per 1000 developed any of the 20 conditions than did uninfected controls.  


Oh, well, these are just old fogies, right?  The mean age was 61.4 with a standard deviation of 15.6 years.  The hazard ratio for those older than 65 versus those under 65 were only slightly different (only one outcome had 95% CIs that didn't overlap).  Since, say, children weren't in the study group, there is no evidence one way or the other about their cardiac health risks over the long term.

Quote:The risks were evident regardless of age, race, sex and other cardiovascular risk factors, including obesity, hypertension, diabetes, chronic kidney disease and hyperlipidemia; they were also evident in people without any cardiovascular disease before exposure to COVID-19, providing evidence that these risks might manifest even in people at low risk of cardiovascular disease. 


It is hard to imagine that one grows out of this risk, or that it is healed.  I suspect the hazard ratios will increase over time.
Reply
#2
The heart info illustrates yet again all the tendrils beyond "flu-like" that COVID brings.   I also saw an article today that it can degrade the placenta.   I"ll post if I find again.
Reply
#3
Here's the paper.
https://meridian.allenpress.com/aplm/art...ufficiency

and a news article that covers more than just the latest paper.
https://abcnews.go.com/Health/wireStory/...s-82805665

Quote:A Centers for Disease Control and Prevention report in November found that among pregnant U.S. women infected with COVID-19, about 1 in 80 deliveries was a stillbirth — the loss of a fetus anytime after 20 weeks. That’s compared with 1 in 155 among uninfected women.
Ouch, double the rate of stillbirths.
"The magnitude of association was higher during the period of SARS-CoV-2 B.1.617.2 (Delta) variant predominance than during the pre-Delta period."

A quick look at the CDC report suggests the criteria for inclusion was a diagnosis of COVID-19 at hospitalization, not evidence of COVID-19 earlier in the pregnancy. Also, it appears fetal deaths at gestational age of less than 20 weeks were excluded as being counted as stillbirths. (So, even more pregnancies may end as a result of COVID than counted as stillbirths.)
During Delta, the relative risk was 4.0, 2.5x as much as before Delta (1.5).

I didn't see data on severity of the mother's COVID or how long she had it before stillbirth.
Reply


Forum Jump:


Users browsing this thread: 1 Guest(s)