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Clinical trials
COVID-19 is a new disease for which initially there were no effective treatments.  In the first year, much has been learned about the disease and how the human body reacts to it.

If you get COVID-19 now, you don't have to lie there and let the disease run its course.  There are many trials that may improve your chances to have a mild case, or avoid the worst outcomes.  There are therapeutic medicines that may help.  You are within your rights to demand that your doctors consider these medications or trials.

If you think you may have COVID, talk to your doctor asap and ask him about therapeutic drugs.  Don't wait for him/her to call you back, maybe the next day, or put you off with "Let's see what the test says first."   It is your life and your health.  Get answers quickly from some health professional.  Time is of the essence.  The sooner you get a therapeutic, the better chance you have to have an inconsequential case.

You may have your best chance of getting some treatment if you know what's out there and try to get yourself into a trial.
You can research the trials near your home or hospital at
As I type this, there are over 2,200 clinical trials related to COVID that are currently recruiting subjects.  Many of these trials take place in a number of communities.

(Note that many trials will give placebos to some patients, so the trial can distinguish the benefits of a drug versus not getting the drug.  While the availability of therapeutic drugs is limited, even a 50% chance of getting a drug may be better than taking no drugs.)

Some of these trials of therapeutic drugs may require you to be admitted to the trial even before you get test results back from your local health agency.  SO BE QUICK to seek a trial. Some trials require you to be in the trial by your third day of symptoms.   Preferably, know what trials you may want if you get sick.  If you get sick, ask a relative or friend to research what is available and make quick recommendations.  Whether you are the patient, spouse, parent or child of the patient, you will probably be to frazzled and stressed to be able to think clearly.

Other medications may help after the disease has progressed.  If you didn't attack COVID early, there are still options.

Even if you don't have COVID-19 now, there may be clinical studies that can help you.  As I write this, there are still vaccine trials going on.  There are trials for prophylactic medication for those exposed to COVID-19.  There are trials for household members of COVID cases.  There are trials for those who have had COVID-19.

Clinical trials are not without their risks.  Do consider the issues about whatever trial you may consider.
On this topic, Pfizer and Moderna must now have way more data on their vaccines. I suppose that the trial data is their own and they have no obligation to release it until they request a change of status (say, to "approved"). It sure would be nice to see if the tiny numbers we saw were updated with the current stats.
Another thing about clinical trials. Preventing disease may not be the best measure. I suggest (1) reducing lethality, and (2) reducing spread. The first is easy to measure, I doubt the second is.

New cancer drug effective in vitro against Covid-19.
The title is "Host-directed therapies against early-lineage SARS-CoV-2 retain efficacy against B.1.1.7 variant"

For the rest of us, "host-directed" means, if I understand it correctly, that the therapy makes changes in the host (the person with COVID) that results in efficacy against the virus. The idea is that the virus is less likely to evolve to avoid the therapy. So, the title means that therapies developed against virus from back in the first part of 2020 are still effective against the recent B.1.1.7.

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