01-25-2021, 03:41 PM
The vaccines are all going to continue being highly efficacious. A 6 fold reduction in neutralizing antibodies may make zero clinical difference, and antibodies are just one small part of the picture. Your immune system generates a robust response to the whole spike protein so even with several mutations, the vaccines should be in good shape with antibodies and T-cells directed at different parts of the spike protein.
If we did get a bad enough variant, a tweak to the mRNA vaccines would take days to design and could probably be released without a full 30k person trial.
If we did get a bad enough variant, a tweak to the mRNA vaccines would take days to design and could probably be released without a full 30k person trial.