Share on Facebook Share on Twitter

Thread Rating:
  • 0 Vote(s) - 0 Average
  • 1
  • 2
  • 3
  • 4
  • 5
Looking ahead on vaccines
#13
(08-11-2021, 07:51 AM)Hurlburt88 Wrote: https://www.npr.org/2021/08/10/102650055...ccines-are
Here's the actual paper (pre-print)
Immune Correlates Analysis of the mRNA-1273 COVID-19 Vaccine Efficacy Trial

Quote:In conclusion, the result that all evaluated binding and neutralizing antibody markers strongly inversely correlated with COVID-19 risk, and directly correlated with vaccine efficacy, as well as the result that a substantial proportion of the overall vaccine efficacy was mediated through neutralizing antibody levels, adds evidence toward establishing an immune marker surrogate endpoint for COVID-19 vaccines.

As I understand it, they were studying the blood of those that got the Moderna vaccine (in Moderna trials, not the general population) and seeing which individuals got COVID subsequently.    They were looking for markers that show how effective the vaccine will be (for the individual, and for the group) at reducing the chance of getting COVID.   Finding such markers would allow faster & smaller trials for vaccine testing. Rather than wait 4 months to see how many got COVID, they could wait a shorter amount of time (57 or 29 days) and see whether the markers are present.

The didn't say it, but I would bet this also allows for predicting that the vaccine's protectiveness has faded and that it is time to get boosters.

Reply


Messages In This Thread
Looking ahead on vaccines - by Hurlburt88 - 05-03-2021, 09:33 AM
RE: Looking ahead on vaccines - by M_T - 05-05-2021, 02:45 AM
RE: Looking ahead on vaccines - by ChrisGreene - 05-05-2021, 02:28 PM
RE: Looking ahead on vaccines - by Hurlburt88 - 05-06-2021, 10:45 AM
RE: Looking ahead on vaccines - by akiddoc - 05-07-2021, 12:47 AM
RE: Looking ahead on vaccines - by M_T - 05-07-2021, 06:57 AM
RE: Looking ahead on vaccines - by M_T - 05-07-2021, 02:16 PM
RE: Looking ahead on vaccines - by 82Card - 05-07-2021, 11:58 PM
RE: Looking ahead on vaccines - by M_T - 05-08-2021, 06:50 PM
RE: Looking ahead on vaccines - by Hurlburt88 - 05-23-2021, 07:36 AM
RE: Looking ahead on vaccines - by Hurlburt88 - 07-04-2021, 06:45 AM
RE: Looking ahead on vaccines - by Hurlburt88 - 08-11-2021, 07:51 AM
RE: Looking ahead on vaccines - by M_T - 08-11-2021, 01:47 PM
RE: Looking ahead on vaccines - by Hurlburt88 - 09-01-2021, 07:20 AM
RE: Looking ahead on vaccines - by M_T - 09-01-2021, 08:48 AM
RE: Looking ahead on vaccines - by Hurlburt88 - 10-04-2021, 06:15 AM
RE: Looking ahead on vaccines - by Hurlburt88 - 11-02-2021, 03:00 PM
RE: Looking ahead on vaccines - by Hurlburt88 - 11-15-2021, 09:19 AM
RE: Looking ahead on vaccines - by Hurlburt88 - 12-05-2021, 08:54 AM
RE: Looking ahead on vaccines - by Hurlburt88 - 12-22-2021, 11:52 AM
RE: Looking ahead on vaccines - by Hurlburt88 - 12-23-2021, 09:36 AM

Forum Jump:


Users browsing this thread: 1 Guest(s)