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Vaccine effectiveness over time; Including heterogenous boosters
The document "COVID-19 vaccine surveillance report, Week 4, 27 January 2022" from the UK Health Security Agency has some graphs on vaccine effectiveness against Delta and Omicron over time for different vaccines & booster combinations when measured for symptomatic disease, hospitalization, death, infection, transmission.  (From the Steve Shafer Feb. 1 COVID update)

There are other good data in the report.  For instance, % and amount of antibodies in blood donations in UK by age and month (lowest (9%) in 70+; highest(34%) in  17-20yo).  Pregnancy outcomes.

BNT162b2 = Pfizer;  mRNA-1273 = Moderna
Apparently in the UK, the Moderna booster was the half-dose as in the US.

Notice the fall off of the booster over time versus the original doses over time.

Symptomatic disease.
[Image: VE-symp-Ill-Pfizer.png] 

 [Image: VE-symp-Ill-Moderna.png] 

[Image: VE-hosp-Pfizer.png]
(no Moderna)
THanks for posting.   I am struggling to find logic for someone to decide to get vaccinated and then pass on the booster, short of a concerning reaction.
I think people feel they were promised immunity if they just got the 2 vaccinations. Now they are being told that's not enough, get a booster. (And, we're already hearing that we'll need another.)

Looking back, I certainly wish the CDC had made it clear that the "full vaccination" was to protect you "for now". But they had to sell it so hard, they over-promised, or at least, that's how I heard what they said.

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