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Breakthrough (post-vaccine) Infections - Printable Version

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Breakthrough (post-vaccine) Infections - M_T - 03-24-2021

We're starting to see decent numbers on post-vaccination COVID infections.  The numbers seem pretty good to me, so far.

UConn women's basketball team coach was detected as having COVID as part of his team's testing protocol before the NCAA tournament.  This was a week after his 2nd shot (I haven't seen which vaccine, but only Moderna & Pfizer were available when he started), which precludes his case being considered as after full vaccination (2 weeks post 2nd shot) but would have contributed to the approximately 5% cases after vaccination (Moderna showed 94-95% effectiveness beginning 2 weeks after the first shot.)   In interviews, he said that he felt the same as any other time, suggesting he had no symptoms.  If so, then likely his case would not have been discovered in the clinical trials.    [It isn't that 5% of those vaccinated will get the illness; it is that a vaccinated individual has a 1/20th chance of getting COVID relative to an unvaccinated individual.]

I believe that the clinical trials would not normally have detected asymptomatic infections.  The clinical trials definitely did not attempt to detect whether those vaccinated were more or less likely to spread the virus.

"Minnesota reports 89 COVID-19 cases in vaccinated individuals" indicates 89 cases in an estimated 800K fully vaccinated individuals.  Unfortunately, these numbers are almost meaningless as they don't give the number of person years of exposure by the individuals nor the infection rate per person year for the unvaccinated population.


Quote:Dr. Andrew Olson said, "It's more than an anecdotal observation at this point" that the breakthrough cases treated at M Health Fairview hospitals in the Twin Cities area have had better outcomes.Â