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Full Version: Different Israeli study on 4th dose
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Another set of results on the 4th dose of Pfizer or Moderna in Israel
  Efficacy of a Fourth Dose of Covid-19 mRNA Vaccine against Omicron

Small study (154 got Pfizer, 120 got Moderna).  All had 3 doses of Pfizer previously.  Study lasted to 3 weeks post vaccination.  Comparison of infections from 1 week to 3 weeks post vaccination.  Study & control individuals were supposed to have weekly PCR tests.   (This was during the very high infection rate period of January 2022)


Quote:Overall, 25.0% of the participants in the control group were infected with the omicron variant, as compared with 18.3% of the participants in the BNT162b2 group and 20.7% of those in the mRNA-1273 group. Vaccine efficacy against any SARS-CoV-2 infection was 30%

Most infected health care workers reported negligible symptoms, both in the control group and the intervention groups. However, most of the infected participants were potentially infectious, with relatively high viral loads 



That's a high percentage of everyone getting infected:  25% had an infection during that 2 week period.
To me, becoming hard to see incremental benefit.  Nonetheless, I did get a 2nd booster.